We support the development of a more verifiable, more open, and fairer ecosystem for science and scientists. The Desci Foundation is an independent organization of leading scientists and innovators. We are dedicated to exploring the potential of applying new technologies, incentives, processes, and funding models to the scientific ecosystem. Our mission is to support high-quality science by: 1) Carefully assessing the opportunities and risks of applying new technologies, incentives, processes, and funding models to the scientific ecosystem. 2) Guiding and supporting the development and implementation of new ways to enable high-quality, replicable science. 3) Bringing scientists & innovators together. 4) Enfranchising a group of stakeholders to steer the emerging ecosystem of decentralized science, such as that built by DeSci Labs. We are particularly passionate about projects that support: 1) Open science practices such as pre-registered analysis plans, open repositories, accessible code, and FAIR data. 2) Replication studies. 3) Open peer review. 4) Fair rewards for the work that scientists are doing. 5) Efficient funding models for research.